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#12 Improving signal detection with vigiGroup – Jim Barrett & Joe Mitchell
Manage episode 424661257 series 2749727
Statistical tools can not only cut through the noise in large pharmacovigilance databases. They can also help identify more clinically meaningful patterns in the data. Uppsala Monitoring Centre’s Jim Barrett and Joe Mitchell explain how vigiGroup, a novel clustering algorithm, can bring value to signal detection.
Tune in to find out:
- What the limits of traditional disproportionality analysis are
- How clustering algorithms can improve current signal detection practices
- How vigiGroup has helped monitor the safety of COVID-19 vaccines so far
Want to know more?
- By applying vigiGroup to COVID-19 vaccine reports in VigiBase, our Research team was able to identify a number of potential safety signals. Find out more in this poster or in this presentation.
- Details on how the vigiGroup method was developed and tested can be found in the original publication in Artificial Intelligence in Medicine.
- Appendicitis was one of the possible safety signals for the COVID-19 vaccines identified with vigiGroup.
For more on signal detection at Uppsala Monitoring Centre, visit the Signal Work section on our website or listen to this interview with Helena Sköld and Annette Rudolph on vaccine pharmacovigilance.
Join the conversation on social media
Follow us on X, LinkedIn, or Facebook and share your thoughts about the show with the hashtag #DrugSafetyMatters.
Got a story to share?
We’re always looking for new content and interesting people to interview. If you have a great idea for a show, get in touch!
About UMC
Read more about Uppsala Monitoring Centre and how we work to advance medicines safety.
52 episoder
Manage episode 424661257 series 2749727
Statistical tools can not only cut through the noise in large pharmacovigilance databases. They can also help identify more clinically meaningful patterns in the data. Uppsala Monitoring Centre’s Jim Barrett and Joe Mitchell explain how vigiGroup, a novel clustering algorithm, can bring value to signal detection.
Tune in to find out:
- What the limits of traditional disproportionality analysis are
- How clustering algorithms can improve current signal detection practices
- How vigiGroup has helped monitor the safety of COVID-19 vaccines so far
Want to know more?
- By applying vigiGroup to COVID-19 vaccine reports in VigiBase, our Research team was able to identify a number of potential safety signals. Find out more in this poster or in this presentation.
- Details on how the vigiGroup method was developed and tested can be found in the original publication in Artificial Intelligence in Medicine.
- Appendicitis was one of the possible safety signals for the COVID-19 vaccines identified with vigiGroup.
For more on signal detection at Uppsala Monitoring Centre, visit the Signal Work section on our website or listen to this interview with Helena Sköld and Annette Rudolph on vaccine pharmacovigilance.
Join the conversation on social media
Follow us on X, LinkedIn, or Facebook and share your thoughts about the show with the hashtag #DrugSafetyMatters.
Got a story to share?
We’re always looking for new content and interesting people to interview. If you have a great idea for a show, get in touch!
About UMC
Read more about Uppsala Monitoring Centre and how we work to advance medicines safety.
52 episoder
Alla avsnitt
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1 #35 Veterinary pharmacovigilance part 2 – James Mount 41:42
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1 #34 Veterinary pharmacovigilance, Part I – James Mount 47:21
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1 #33 Narrative fields and signal assessors, an exploratory study – Joana Félix and Alem Zekarias 38:43
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1 #32 Pharmacovigilance in older adults – Giovanni Furlan 47:51
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1 #31 A guide to reporting disproportionality analyses – Michele Fusaroli and Daniele Sartori 42:45
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1 Uppsala Reports Long Reads – Weeding out duplicates to better detect side effects 25:02
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1 Uppsala Reports Long Reads – Ensuring trust in AI/ML when used in pharmacovigilance 30:18
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1 #30 Preventing and reporting medication errors – Rabat CC & UMC 33:58
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1 #29 When medicines change our behaviour – Michele Fusaroli 30:30
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1 #28 Catching black swans – François Montastruc 27:21
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1 #27 When drugs damage the liver – Rita Baião 28:30
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1 #26 What's trending in pharmacovigilance? – Angela Caro 28:06
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1 #25 A week in the name of medicines safety – part 2 33:13
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1 #24 A week in the name of medicines safety – part 1 27:09
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1 Uppsala Reports Long Reads – The colour of signals 33:59
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