Bridging the Gap for Women's Health with Dr. Mackenzie from Reputable Health

Renee Belz & Lauren Sambataro

Join us for this episode with Dr. Mackenzie De Jesus, the head of the research team at Reputable Health, to explore the growing need for more research in women's health. Dr. Mackenzie highlights the historical gaps in healthcare research for women and the impact this has had on diagnosis, treatment, and overall well-being. She shares how Reputable Health is driving change by focusing on comprehensive studies that address these disparities, as well as what she has learned through tracking data like HRV and respiratory rate amongst women. This episode sheds light on the innovative work being done to close the gender gap in medical research and improve health outcomes for women everywhere.

Dr. Mackenzie De Jesus, DHSc, MS leads the research team at Reputable Health with extensive expertise in health science, experimental psychology, and clinical research. She holds a Doctorate of Health Science from A.T. Still University and a Master’s degree in Experimental Psychology from Nova Southeastern University. Dr. De Jesus has a strong background in designing and executing clinical trials, particularly in functional medicine and digital health. Her experience includes serving as the Associate Director of Research at Mymee, Inc., where she led program evaluations for digital health projects, managed data, and developed research strategies to improve health outcomes in nonresponders with rheumatic autoimmunity, who despite undergoing current standard of care, remain symptomatic. Mackenzie has also been involved in neurobehavioral research at the University of Pittsburgh and has developed health interventions, such as heart rate variability biofeedback protocols for diverse patient populations, including post-9/11 veterans. It is her passion to bridge the gaps between what we know about human health and physiology and the applications used to achieve health-based outcomes, which is one of her goals at Reputable.

SHOW NOTES:

0:51 Welcome to the show!

2:01 Healthspan Summit

3:16 Reputable Health App

4:51 Dr. Mackenzie De Jesus’ Bio

5:24 Welcome her to the podcast!

6:38 How can we bridge the gap for women’s health research?

8:03 Biggest bucket items affecting female physiology

9:53 How do we control for female variability?

13:55 Increasing research participation

15:32 Top Biomarkers to watch for women

16:53 About Reputable Health App

20:22 *Cycle Care Ad*

23:02 Tracking the female cycle & HRV

26:03 Sympathetic vs Parasympathetic

29:40 Validating commercial products with Reputable

31:20 Protecting personal privacy & data

36:06 The benefits and accessibility of wearables

40:05 Using the App with OURA & Whoop

41:41 Respiratory Rates & Resonant Breathing

47:12 What you can expect with Reputable

53:28 Her final piece of advice

54:04 Where to find her & Reputable

54:31 Thanks for tuning in!

RESOURCES:

App: Reputable Health

Email: [e-mail]

Instagram: ReputableHealth

Instagram: Dr. Mackenzie

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