Bästa CRISPR Journal podcaster (2024)

1
AI for Pediatric Pseudopapilledema and True Papilledema 15:12

6d ago15:12

15:12

Can artificial intelligence distinguish between pseudopapilledema and true papilledema in children? Dr. Drew Carey interviews author Dr. Melinda Y. Chang on whether AI can be used to improve the diagnostic process in children with abnormal optic nerves and concern for elevated intracranial pressure. From her Ophthalmology Science article, “Artifici…

1
Evaluating Primary Treatment for People with Advanced Glaucoma 24:38

20d ago24:38

24:38

Does primary trabeculectomy or medical treatment produce better outcomes in terms of quality of life, clinical effectiveness, and safety in patients with advanced glaucoma? Dr. Drew Carey interviews Dr. Anthony J. King on the results of his recent study asking this question published in Ophthalmology, “Evaluating Primary Treatment for People with A…

1
Ophthalmology Education in Medical Schools 28:28

1M ago28:28

28:28

How has ophthalmology medical education changed over time in medical school curriculums? Dr. Edmund Tsui speaks with Drs. Ashish Agar and Sascha Spencer on their review of global trends in medical school ophthalmology education from their Ophthalmology article, “A Systematic Review of Ophthalmology Education in Medical Schools: The Global Decline.”…

1
Adverse Events with Opioids and Ophthalmic Surgery 28:33

2M ago28:33

28:33

Ophthalmologists are not spared from the opioid epidemic. Recent studies have shown that opioids continue to be prescribed after ophthalmic surgeries. Dr. Drew Carey interviews Dr. Matthew R. Starr on his retrospective study published in Ophthalmology, “Hospitalization, Overdose, and Mortality After Opioid Prescriptions Tied to Ophthalmic Surgery.”…

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CRISPR Assay for Fungal Keratitis 23:41

2M ago23:41

23:41

The RID-MyC assay, a CRISPR/Cas12a-based test, offers swift and reliable detection of Fungal Keratitis, enhancing diagnostic capabilities at point-of-care settings. Dr. Rajesh Rao interviews Dr. Siddharth Narendran on the development of this assay from his Ophthalmology Science article, “Development and Clinical Evaluation of a CRISPR/Cas12a-Based …

1
Bevacizumab in High-Risk Penetrating Keratoplasty 23:19

3M ago23:19

23:19

Dr. Matt Feng is joined by Dr. Thomas H. Dohlman to discuss the effectiveness of topical and subconjunctival bevacizumab in suppressing vascularization in graft and host bed after high-risk corneal transplantation, from his Ophthalmology Science article “Suppression of Neovascularization by Topical and Subconjunctival Bevacizumab After High-Risk Co…

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Hearing Dysfunction with Teprotumumab 24:31

3M ago24:31

24:31

What does hearing dysfunction have to do with an ophthalmology podcast? Listen up and find out as Dr. Drew Carey interviews Dr. Jamie A. Keen and Dr. Erin M. Shriver on the risks of using teprotumumab to hearing function in treatment of thyroid eye disease. From their article “Frequency and Patterns of Hearing Dysfunction in Patients Treated with T…

1
Recurrent Retinal Redetachment after Cataract Surgery 23:59

3M ago23:59

23:59

Dr. Matt Feng interviews Drs. Bita Momenaei and Jason Hsu on the incidence, timing, risk factors, and outcomes of recurrent retinal detachment after phacoemulsification, from their Ophthalmology Retina article, “Incidence and Outcomes of Recurrent Retinal Detachment after Cataract Surgery in Eyes with Prior Retinal Detachment Repair.” Incidence and…

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Private Equity & Ophthalmology: Spending and Services After Acquisition 27:46

4M ago27:46

27:46

Private equity (PE) firms acquired over 200 ophthalmology and optometry practices in the United States from 2021 through 2019. Dr. Rajesh Rao interviews author Dr. Gary Joseph Lelli about the implications of this trend and influence of PEs on care use and spending, from his Ophthalmology article, “Association of Private Equity Firm Acquisition of O…

1
Efficacy of Carbonic Anhydrase in Patients with X-Linked Retinoschisis 20:02

5M ago20:02

20:02

X-linked retinoschisis is a relatively common inherited retinal degenerative disease that almost exclusively affects males. No curative medical therapy is available for this condition, however topical and oral carbonic anhydrase inhibitors have been used for the management of cystoid fluid collections. Dr. Drew Carey interviews authors Dr. Jonathan…

1
Aqueous Macrophages Contribute to Conserved CCL2 & CXCL10 Gradients in Uveitis 16:44

5M ago16:44

16:44

Uveitis is a heterogenous group of inflammatory eye diseases for which current cytokine-targeted immune therapies are effective for only a subset of patients. Dr. Edmund Tsui is joined by Dr. Lynn M. Hassman and MD/PhD student Joseph B. Lin to explore potential common underlying mechanisms that exist for immune cell recruitment in uveitis in their …

1
Vitamin A Deficiency Retinopathy 17:03

6M ago17:03

17:03

Vitamin A deficiency is the leading cause of preventable childhood blindness worldwide, but how does this deficiency present itself in a clinical setting? Dr. Drew Carey finds out as he interviews Dr. Nieraj Jain, author of “Characteristics of Vitamin A Deficiency Retinopathy at a Tertiary Referral Center in the United States.” Characteristics of V…

1
Outcomes and Complications after IOL Exchange 35:19

6M ago35:19

35:19

An analysis of the IRIS® Registry shows IOL exchanges are increasing over time with vision improving 60% of the time, but worse visual outcomes associated with greater age, worse baseline vision, Black race, Hispanic ethnicity, Medicaid insurance, smoking, and concurrent vitrectomy. Dr. Matt Feng sits with authors Drs. David F. Chang and Fasika A. …

1
Ophthalmology Workforce Projections, 2020-2035 15:15

7M ago15:15

15:15

The Department of Health and Human Services, Health Resources and Services Administration’s Health Workforce Simulation Model forecasts a sizeable shortage of ophthalmology supply relative to demand by the year 2035, with substantial geographic disparities. Dr. Edmund Tsui is here with author Dr. Sean T. Berkowitz to breakdown the implications of t…

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The Effect of Scleral Buckle Surgery on Glaucoma Risk 25:53

7M ago25:53

25:53

Scleral buckling is a common surgical procedure for the repair of rhegmatogenous retinal detachment. The association between scleral buckling and angle-closure glaucoma is well-documented. However,the influence of scleral buckling on the development and progression of open-angle glaucoma is less well understood. Dr. Lori Provencher interviews Dr. A…

1
Neuro-Ophthalmology Consultations 32:15

8M ago32:15

32:15

Neuro-ophthalmology consultations are critical to the diagnosis and management in the hospital setting. Prompt consultation prevents diagnostic errors and improves patient outcomes. The scarcity of neuro-ophthalmologists means that the increasing outpatient demand cannot be met, prompting many emergency department referrals by non–neuro-ophthalmolo…

1
Presentation & Outcomes of Acute Syphilitic Posterior Placoid Chorioretinopathy 16:45

8M ago16:45

16:45

Syphilis is often known as the “the great masquerader” because it can mimic symptoms and look like a wide array of other diseases. Dr. Edmund Tsui interviews Dr. Michael Huvard to get to the bottom of how acute syphilitic posterior placoid chorioretinopathy presents itself in eyes and the outcomes for these patients, from his Ophthalmology article …

1
Stem Cell Transplantation and Optic Nerve Regeneration 30:44

9M ago30:44

30:44

Dr. Drew Carey sits down with Dr. Thomas V. Johnson to discuss the work of the RReSTORe Consortium in the field of regenerative medicine as applied to optic neuropathies from his Ophthalmology Science article, “The Retinal Ganglion Cell Repopulation, Stem Cell Transplantation, & Optic Nerve Regeneration (RReSTORe) Consortium.” For more of the Ophth…

1
Cost Drivers of Endothelial Keratoplasty 29:06

9M ago29:06

29:06

Endothelial keratoplasty (EK) procedures have become the preferred method of corneal transplantation in the United States. As the frequency of EKs increase, so do associated costs. Dr. Matt Feng interviews Drs. David S. Portney and Shahzad I. Mian about their recent analysis to assess for differences in surgical costs and surgery length based on ty…

1
Outcomes of Glaucoma Reoperations in the Primary Tube Versus Trabeculectomy 22:56

10M ago22:56

22:56

The Primary Tube Versus Trabeculectomy Study is a multicenter randomized clinical trial comparing the safety and efficacy of tube shunt surgery and trabeculectomy with mitomycin C in eyes without previous ocular surgery. Dr. Lori Provencher sits down with authors Dr. Sara J. Coulon and Dr. Steven J. Gedde to discuss the results of this trial from t…

1
Predictors of Poor Visual Outcome in MOG-related Optic Neuritis 22:15

10M ago22:15

22:15

Myelin oligodendrocyte glycoprotein-related optic neuritis is typically associated with good visual outcome in most patients, but poor outcomes are reported in 15% to 36.8% of patients. Dr. Drew Carey sits down with Dr. Edward Margolin to discuss the possible factors associated with poor outcomes, from his Ophthalmology article, “Predictors of Poor…

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Live at AAO 2023: Six Myths of the Anterior Segment 44:52

10M ago44:52

44:52

Recorded live at AAO 2023 and we’re myth busting common ophthalmologic misconceptions of the anterior segment. Drs. Drew Carey and Matt Feng interview Dr. Todd Margolis on his recent Ophthalmology editorial, “Six Myths of the Anterior Segment: Misunderstandings and Critical Thinking in Ophthalmology.” He shares bonus myths not in the editorial, and…

1
Ophthalmologist Turnover in the United States 18:46

11M ago18:46

18:46

One-third of US ophthalmologists left at least one practice from 2014-2021. What are the factors behind this high turnover rate, how does this affect patient care, and what can be done to stabilize the workforce? Dr. Rajesh Rao interviews Dr. Ravi Parikh about his Ophthalmology article, “Ophthalmologist Turnover in the United States: Analysis of Wo…

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MERIT Trial Results: Intravitreal Therapy for Uveitic Macular Edema 20:55

12M ago20:55

20:55

What treatments are effective for uveitic macular edema? Drs. Nisha R. Acharya and Douglas A. Jabs of the MUST Research Group discuss with Dr. Edmund Tsui the landmark findings of the MERIT Trial in their recent Ophthalmology article, “Intravitreal Therapy for Uveitic Macular Edema—Ranibizumab versus Methotrexate versus the Dexamethasone Implant.” …

1
Infections from Artificial Tears 28:46

1y ago28:46

28:46

News broke in early 2023 of several deaths related to use of contaminated over-the-counter artificial tear products resulting in FDA and CDC warnings and a product recall. Dr. Matt Feng reviews what transpired and discusses lessons learned with Dr. Gary Novack, author of the Ophthalmology editorial, “Infections from Over-The-Counter Artificial Tear…

1
Risk of Pseudophakic Cystoid Macular Edema in Cataract Surgeries 14:51

1y ago14:51

14:51

Cataract surgery is one of the most commonly performed surgeries globally. What are the risk factors for patients developing pseudophakic cystoid macular edema after cataract surgery? Dr. Edmund Tsui sits down with Dr. Ahmed B. Sallam to discuss the findings of his Ophthalmology article, “Risk of Pseudophakic Cystoid Macular Edema in Fellow-Eye Cat…

1
Reduced Cone Density in Multiple Sclerosis 21:27

1y ago21:27

21:27

Does multiple sclerosis contribute to the degeneration of the outer retinal layers? Dr. Drew Carey interviews Dr. Imre Lengyel on his recent Ophthalmology Science article, “Reduced Cone Density Is Associated with Multiple Sclerosis.” Reduced Cone Density Is Associated with Multiple Sclerosis. McIlwaine, Gemma et al. Ophthalmology Science, Volume 3,…

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A Review of RCT Ophthalmic Papers 2020-2021 17:08

1y ago17:08

17:08

How can we improve the design and reporting of ophthalmic randomized controlled trials? Dr. Edmund Tsui discusses this with Dr. Gui-shuang Ying author of Ophthalmology Science’s “Characteristics of Design and Analysis of Ophthalmic Randomized Controlled Trials.” Characteristics of Design and Analysis of Ophthalmic Randomized Controlled Trials. Dong…

1
Performance of ChatGPT in Ophthalmology 26:28

1y ago26:28

26:28

Can ChatGPT pass the OKAP exam? Dr. Matt Feng interviews author Dr. Fares Antaki about the implications of using a language model artificial intelligence in ophthalmology from his Ophthalmology Science article, “Evaluating the Performance of ChatGPT in Ophthalmology: An Analysis of Its Successes and Shortcomings” Evaluating the Performance of ChatG…

1
Central Retinal Artery Occlusion: Time to Presentation & Diagnosis 20:18

1y ago20:18

20:18

Is an eye stroke (CRAO) the same as a brain stroke? What new treatments are available for eye stroke? Dr. Drew Carey sits down with Drs. Aubrey Gilbert and Robin Vora to discuss their Ophthalmology Retina article, Central Retinal Artery Occlusion: Time to Presentation and Diagnosis. Central Retinal Artery Occlusion. Shah, Ronak et al. Ophthalmology…

1
Conversion Rates of Anatomically Narrow Angles to Angle Closure Glaucoma 19:02

1y ago19:02

19:02

Primary angle-closure glaucoma is a leading cause of vision loss, affecting an estimated 20 million people. Dr. Lori Provencher sits down with Dr. Benjamin Xu to discuss the research from his article, “Rates and Patterns of Diagnostic Conversion from Anatomical Narrow Angle to Primary Angle-Closure Glaucoma in the United States.” Rates and Patterns…

1
Relationship between Donor Corneal Endothelial Maturity and Cell Loss 22:03

1+ y ago22:03

22:03

Dr. Matt Feng interviews Drs. Koji Kitazawa and Shigeru Kinoshita about their research on endothelial cell loss after corneal transplantation from their Ophthalmology Science article, “The Biologic Character of Donor Corneal Endothelial Cells Influences Endothelial Cell Density Post Successful Corneal Transplantation.” The Biologic Character of Don…

1
EYEMATE-SC Trial: IOP Measurement via an Implantable Sensor 20:17

1+ y ago20:17

20:17

Dr. Lorraine Provencher interviews Dr. Kaweh Mansouri about the results of his study using EYEMATE-SC sensor to monitor IOP measurements in glaucoma patients. From Ophthalmology’s “EYEMATE-SC Trial: Twelve-Month Safety, Performance, and Accuracy of a Suprachoroidal Sensor for Telemetric Measurement of Intraocular Pressure” EYEMATE-SC Trial: Twelve-…

1
How Ophthalmologists Can Decarbonize Eye Care 20:23

1+ y ago20:23

20:23

In the US, health care is responsible for approximately 8.5% of greenhouse gas. How can we reduce the impact of cataract surgery on our environment? Dr. Edmund Tsui discusses this with Dr. Joel S. Schuman and Dr. Cassandra L. Thiel, authors of “How Ophthalmologists Can Decarbonize Eye Care: A Review of Existing Sustainability Strategies and Steps O…

1
Acanthamoeba Keratitis Risk for Contact Lens Users 25:41

1+ y ago25:41

25:41

What’s the risk of contracting Acanthamoeba keratitis with daily disposable contact lenses compared with daily wear reusable lenses? Dr. Edmund Tsui explores this with Dr. John Dart, author of “Acanthamoeba Keratitis Risk Factors for Daily Wear Contact Lens Users.” Acanthamoeba Keratitis Risk Factors for Daily Wear Contact Lens Users. Carnt, Nicole…

1
BLIP - A Benign Inner Retinal Tumor 15:36

1+ y ago15:36

15:36

In this episode, Dr. Drew Carey interviews Dr. Aaron Nagiel about his recent case series on benign intraretinal tumors and the coining of the term “benign lobular inner nuclear layer proliferation” aka BLIPs. From Ophthalmology’s “Benign Lobular Inner Nuclear Layer Proliferations of the Retina Associated with Congenital Hypertrophy of the Retinal P…

1
Home Monitoring of Glaucoma 21:20

1+ y ago21:20

21:20

Telehealth has become more accessible since the COVID-19 pandemic. But how easily do patients take to home testing and what is the acceptability and feasibility home monitoring of glaucoma? Dr. Lori Provencher discusses this with Dr. Lama A. Al-Aswad, author of “Home Monitoring of Glaucoma Using a Home Tonometer and a Novel Virtual Reality Visual F…

1
Ocular Manifestations of ROSAH Syndrome 21:40

1+ y ago21:40

21:40

What is ROSAH syndrome and how does it affect the visual function of patients with it? Dr. Tsui discusses this with Drs. Laryssa A. Huryn and Shilpa Kodati, authors of the Ophthalmology article, “Ophthalmic manifestations of ROSAH Syndrome, an inherited NF-κB mediated autoinflammatory disease with retinal dystrophy.” Ophthalmic Manifestations of RO…

1
Real-Time Deep Learning in Vitreoretinal Surgery 37:19

1+ y ago37:19

37:19

Artificial Intelligence is changing the way doctors perform surgery. Can a deep learning neural network use real-time intraoperative retinal imaging to improve vitreoretinal microsurgery? Dr. Rajesh Rao discusses the findings of this with Dr. Yannek Leiderman, author of “Feature Tracking and Segmentation in Real Time via Deep Learning in Vitreoreti…

1
Choroidal Neovascularization in Best Vitelliform Macular Dystrophy 29:14

1+ y ago29:14

29:14

Please tell us what you think of our show in a brief 2-minute survey: https://forms.office.com/r/B4rYtvpQad How common is choroidal neovascularization in Best’s disease? Host Dr. Drew Carey and author Dr. Ian C. Han discuss the results of his Ophthalmology Retina article, “Choroidal Neovascularization Is Common in Best Vitelliform Macular Dystrophy…

1
Inappropriate Use of the Term “Papilledema” 19:05

1+ y ago19:05

19:05

Please tell us what you think of our show in a brief 2-minute survey: https://forms.office.com/r/B4rYtvpQad Have you misused the term “papilledema?” Chances are probable as the term is often used incorrectly, even in ophthalmology literature. Dr. Drew Carey discusses the widespread misuse of “papilledema” with Dr. Jonathan Micieli, author of “Inapp…

1
Choroidal Changes after Red Light Therapy 26:58

1+ y ago26:58

26:58

Please tell us what you think of our show in a brief 2-minute survey: https://forms.office.com/r/B4rYtvpQad Red Light Therapy has emerged as a new treatment for myopia control. Dr. Matthew Feng sits down with Dr. Mingguang He to discuss these advances from his recent Ophthalmology article, “Longitudinal Changes and Predictive Value of Choroidal Thi…

1
Alcohol Intake and Exfoliation Glaucoma Risk 20:59

1+ y ago20:59

20:59

Does alcohol consumption contribute to the risk of exfoliation glaucoma? And should you be tracking your drinks in grams instead of ounces? Drs. Lori Provencher and Drew Carey interview Drs. Akiko Hanyuda, Louis Pasquale, and Jae Hee Kang from their Ophthalmology article, “Long-term Alcohol Consumption and Risk of Exfoliation Glaucoma or Glaucoma S…

1
rhNGF for Stage 1 Neurotrophic Keratopathy 16:01

1+ y ago16:01

16:01

Is recombinant Human Nerve Growth Factor an effective treatment for Stage 1 Neurotrophic Keratopathy? Dr. Drew Carey discusses this with Dr. Pedram Hamrah author of Ophthalmology’s “Efficacy of Recombinant Human Nerve Growth Factor in Stage 1 Neurotrophic Keratopathy.” Efficacy of Recombinant Human Nerve Growth Factor in Stage 1 Neurotrophic Kerato…

1
Extramacular Drusen in AMD 33:39

2y ago33:39

33:39

AREDS2 is the gift that keeps on giving. Drs Drew Carey and Rajesh Rao team up to interview Dr. Amitha Domalpally on the role of extramacular drusen in AMD from her Ophthalmology Retina article, “Extramacular Drusen and Progression of Age-Related Macular Degeneration.” Extramacular Drusen and Progression of Age-Related Macular Degeneration. Domalpa…

1
Retinal Ischemic Perivascular Lesions 23:37

2y ago23:37

23:37

What are RIPLs and how are they a detector of cardiovascular disease? Dr. Edmund Tsui finds out from Dr. Mathieu F. Bakhoum, author of “Retinal Ischemic Perivascular Lesions, a Biomarker of Cardiovascular Disease” in Ophthalmology Retina. Retinal Ischemic Perivascular Lesions, a Biomarker of Cardiovascular Disease. Madala, Samantha et al. Ophthalmo…

1
Sex Differences in Medicare Reimbursements 12:49

2y ago12:49

12:49

Dr. Lori Provencher discusses the disparity in Medicare reimbursements between male and female ophthalmologists with Dr. Nazlee Zebardast, author of “Sex-Based Differences in Medicare Reimbursements among Ophthalmologists Persist across Time.” Sex-Based Differences in Medicare Reimbursements among Ophthalmologists Persist across Time. Halawa, Omar …

1
An Aqueous Tap for Lymphoma Diagnosis 41:38

2y ago41:38

41:38

Dr. Rajesh Rao speaks with his coauthors Drs. Hakan Demirci and Noah Brown about their Ophthalmology Retina article, “Aqueous Humor–Derived MYD88 L265P Mutation Analysis in Vitreoretinal Lymphoma.” Aqueous Humor–Derived MYD88 L265P Mutation Analysis in Vitreoretinal Lymphoma. Demirci, Hakan et al. Ophthalmology Retina. In press.…

1
Fernlike Leakage on Ultrawide-field Fluorescein Angiography 19:09

2y ago19:09

19:09

Dr. Edmund Tsui interviews author Dr. David Sarraf on his recent Ophthalmology Retina article, “Clinical and Morphologic Characteristics of Perivenular Fernlike Leakage on Ultrawide-field Fluorescein Angiography” Clinical and Morphologic Characteristics of Perivenular Fernlike Leakage on Ultrawide-field Fluorescein Angiography. Ramtohul, Prithvi et…

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Live at AAO 2022 with Dr. Nisha Acharya 39:57

2y ago39:57

39:57

Recorded in front of a live audience at the AAO 2022 Annual Meeting in Chicago. Join a full panel of our hosts as they interview Dr. Nisha Acharya about her recent Ophthalmology article, “Association between Immunosuppressive Drugs and Coronavirus Disease 2019 Outcomes in Patients with Noninfectious Uveitis in a Large US Claims Database,” and take …

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