TWiV 916: COVID-19 clinical update #122 with Dr. Daniel Griffin

This Week in Virology

In COVID-19 clinical update #122, Dr. Griffin discusses vaccine availability and coverage among children, post-infection health impairments in children and adolescents, infection detection using salvia and nasopharyngeal samples, effectiveness of vaccines during delta dominance, durability of vaccine against severe outcomes, concern in the postvaccination era, infection rebound after Paxlovid & Molnupiravir, lack of improvement after adding ivermectin to standard care, duration of shedding of virus, how thromboprophylaxis reduces thromboembolism but increases major bleeding, multi-lineage neural and myelin dysregulation caused by infection, and the association between vaccination and post-acute infection.

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Links for this episode

• The next epidemic may be here (STAT)
• Vaccine availability and coverage among children (CDC)
• Post-infection health impairments in children & adolescents (Pediatrics)
• Infection detection using saliva & nasopharyngeal samples (Journal of Medical Virology)
• Effectiveness of vaccines during Delta dominance (The Lancet)
• Durability of vaccine against severe outcomes (The Lancet)
• Don’t rush to change COVID vaccines (STAT)
• Concern in the postvaccination era (Immunity, Inflammation and Disease)
• Infection rebound after Paxlovid & Molnupiravir (medRxiv)
• No improvement after Ivermectin usage (ACP)
• Duration of shedding of virus (New England Journal of Medicine)
• Infectious viral load vaccinated vs unvaccinated (Nat Med)
• Thromboprophylaxis reduces thromboembolism (NIH)
• Multi-lineage neural cell and myelin dysregulation caused by infection (Cell)
• Association between vaccination and post-acute infection (JAMA)
• Contribute to FIMRC fundraiser at PWB
• Dr. Griffin’s treatment guide (pdf)
• Letters read on TWiV 916
• Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [e-mail]