A myriad of AI, science, and technology experts explore the real challenges and enormous opportunities facing entrepreneurs who are building the future of health. Raising Health, a podcast by a16z Bio + Health and hosted by Kris Tatiossian and Olivia Webb, dives deep into the heart of biotechnology and healthcare innovation. Join veteran company builders, operators, and investors Vijay Pande, Julie Yoo, Vineeta Agarwala, and Jorge Conde, along with distinguished guests like Mark Cuban, Greg ...
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InnehÄll tillhandahÄllet av Jon Chee. Allt poddinnehÄll inklusive avsnitt, grafik och podcastbeskrivningar laddas upp och tillhandahÄlls direkt av Jon Chee eller deras podcastplattformspartner. Om du tror att nÄgon anvÀnder ditt upphovsrÀttsskyddade verk utan din tillÄtelse kan du följa processen som beskrivs hÀr https://sv.player.fm/legal.
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𧏠David Li - Meliora Therapeutics - Part 4 | Mechanism Identification in Biotech | AI & ML in Drug Development | Creating a New Method for Drug Discovery | Fundraising for Meliora | Building a Foundational Startup Team
MP3•Episod hem
Manage episode 428387618 series 3461709
InnehÄll tillhandahÄllet av Jon Chee. Allt poddinnehÄll inklusive avsnitt, grafik och podcastbeskrivningar laddas upp och tillhandahÄlls direkt av Jon Chee eller deras podcastplattformspartner. Om du tror att nÄgon anvÀnder ditt upphovsrÀttsskyddade verk utan din tillÄtelse kan du följa processen som beskrivs hÀr https://sv.player.fm/legal.
As a podcast listener, you can redeem exclusive discounts with a growing list of biotech vendors and get $500 off your first equipment lease by using promo code âTBSPâ on https://www.excedr.com/rewards.
Part 4 of 4.
My guest for this weekâs episode is David Li, CEO and co-founder of Meliora Therapeutics. Meliora's goal is to develop life-saving cancer therapies using cutting-edge science and machine learning. The company derives a comprehensive picture of how drugs interact with cancer biology by combining biofunctional readouts from numerous modalities using advanced machine learning and other computational techniques.
Before Meliora, David was Chief Business Officer at Everest Detection, an early detection liquid biopsy startup, and led commercial operations at Benchling, a life sciences software platform valued at $6 billion with over $500 million in funding.
David started his career in Goldman Sachs Healthcare Investment Banking Group and KKR's Private Equity Group, advising and investing in transactions exceeding $10 billion. His diverse financial and life sciences background offers valuable insights for founders.
Join us this week and hear about:
- Davidâs transition from private equity to co-founding Meliora and using AI/ML in drug development
- His fundraising experiences for Meliora and current outlook on the fundraising landscape in 2024
- His advice for aspiring entrepreneurs and reflections on âthinking bigâ in biotech
- Identifying mischaracterized mechanisms of action and establishing Meliora as a drug development company and computational platform
Please enjoy my conversation with David Li.
Timestamps:
00:28 Intro
02:00 Jason Scheltzer identifies mechanisms of action, the beginnings of Meliora
05:08 David meets Jason Scheltzer, forming Meliora with a thesis, as David becomes founding CEO and initial fundraising begins
07:20 Davidâs serendipitous meeting with Jason, getting on board as more than an investor
09:16 Building the early founding team at Meliora, establishing Meliora as a drug company
12:05 How Meliora is disrupting the status quo in drug discovery and development
17:24 Davidâs approach to building an internal pipeline and BD partnerships
19:49 Davidâs experience fundraising and his outlook on fundraising in 2024
22:21 Meloriaâs 2-year vision, transitioning from Seed to Series A
24:03 Shoutouts and advice to 21-year old self
26:23 Outro
Find Our Guest, David Li, at these links:
Find Our Host, Jon Chee, at these links:
Social & Website
LinkedIn: https://www.linkedin.com/company/excedr/
Youtube: https://www.youtube.com/@excedr
Instagram: https://www.instagram.com/excedr_inc
Twitter: https://twitter.com/ExcedrInc
Facebook: https://www.facebook.com/excedr
TikTok: https://www.tiktok.com/@excedr
Podcast Website: https://www.thebiotechstartupspodcast.com/
Enriched Notes:
Topics Mentioned:
Benchling https://www.benchling.com/
Meliora Therapeutics https://www.melioratherapeutics.com/
Everest Detection https://everestdetection.com/
AstraZeneca https://www.astrazeneca.com/
Tagrisso https://www.tagrisso.com/
Drug candidates that were mischaracterized https://ergobio.substack.com/p/meliora-therapeutics-is-building
Series A, B, & C Rounds https://www.excedr.com/resources/series-funding-explained
Biotech Fundraising https://www.excedr.com/resources/biotech-startup-funding-options
Computational Platforms in Biotech https://www.nfx.com/post/bioplatforms-computational-biology
People Mentioned:
Jason Sheltzer https://www.linkedin.com/in/jason-sheltzer-ba0086234/
Joan Smith https://www.linkedin.com/in/joanclarasmith/
Claudio Chuaqui https://www.linkedin.com/in/claudio-chuaqui-5612381/
Andrew Coopersmith https://www.linkedin.com/in/andrew-s-coopersmith/
The Biotech Startups Podcast is handcrafted by our friends over at: fame.so
88 episoder
MP3•Episod hem
Manage episode 428387618 series 3461709
InnehÄll tillhandahÄllet av Jon Chee. Allt poddinnehÄll inklusive avsnitt, grafik och podcastbeskrivningar laddas upp och tillhandahÄlls direkt av Jon Chee eller deras podcastplattformspartner. Om du tror att nÄgon anvÀnder ditt upphovsrÀttsskyddade verk utan din tillÄtelse kan du följa processen som beskrivs hÀr https://sv.player.fm/legal.
As a podcast listener, you can redeem exclusive discounts with a growing list of biotech vendors and get $500 off your first equipment lease by using promo code âTBSPâ on https://www.excedr.com/rewards.
Part 4 of 4.
My guest for this weekâs episode is David Li, CEO and co-founder of Meliora Therapeutics. Meliora's goal is to develop life-saving cancer therapies using cutting-edge science and machine learning. The company derives a comprehensive picture of how drugs interact with cancer biology by combining biofunctional readouts from numerous modalities using advanced machine learning and other computational techniques.
Before Meliora, David was Chief Business Officer at Everest Detection, an early detection liquid biopsy startup, and led commercial operations at Benchling, a life sciences software platform valued at $6 billion with over $500 million in funding.
David started his career in Goldman Sachs Healthcare Investment Banking Group and KKR's Private Equity Group, advising and investing in transactions exceeding $10 billion. His diverse financial and life sciences background offers valuable insights for founders.
Join us this week and hear about:
- Davidâs transition from private equity to co-founding Meliora and using AI/ML in drug development
- His fundraising experiences for Meliora and current outlook on the fundraising landscape in 2024
- His advice for aspiring entrepreneurs and reflections on âthinking bigâ in biotech
- Identifying mischaracterized mechanisms of action and establishing Meliora as a drug development company and computational platform
Please enjoy my conversation with David Li.
Timestamps:
00:28 Intro
02:00 Jason Scheltzer identifies mechanisms of action, the beginnings of Meliora
05:08 David meets Jason Scheltzer, forming Meliora with a thesis, as David becomes founding CEO and initial fundraising begins
07:20 Davidâs serendipitous meeting with Jason, getting on board as more than an investor
09:16 Building the early founding team at Meliora, establishing Meliora as a drug company
12:05 How Meliora is disrupting the status quo in drug discovery and development
17:24 Davidâs approach to building an internal pipeline and BD partnerships
19:49 Davidâs experience fundraising and his outlook on fundraising in 2024
22:21 Meloriaâs 2-year vision, transitioning from Seed to Series A
24:03 Shoutouts and advice to 21-year old self
26:23 Outro
Find Our Guest, David Li, at these links:
Find Our Host, Jon Chee, at these links:
Social & Website
LinkedIn: https://www.linkedin.com/company/excedr/
Youtube: https://www.youtube.com/@excedr
Instagram: https://www.instagram.com/excedr_inc
Twitter: https://twitter.com/ExcedrInc
Facebook: https://www.facebook.com/excedr
TikTok: https://www.tiktok.com/@excedr
Podcast Website: https://www.thebiotechstartupspodcast.com/
Enriched Notes:
Topics Mentioned:
Benchling https://www.benchling.com/
Meliora Therapeutics https://www.melioratherapeutics.com/
Everest Detection https://everestdetection.com/
AstraZeneca https://www.astrazeneca.com/
Tagrisso https://www.tagrisso.com/
Drug candidates that were mischaracterized https://ergobio.substack.com/p/meliora-therapeutics-is-building
Series A, B, & C Rounds https://www.excedr.com/resources/series-funding-explained
Biotech Fundraising https://www.excedr.com/resources/biotech-startup-funding-options
Computational Platforms in Biotech https://www.nfx.com/post/bioplatforms-computational-biology
People Mentioned:
Jason Sheltzer https://www.linkedin.com/in/jason-sheltzer-ba0086234/
Joan Smith https://www.linkedin.com/in/joanclarasmith/
Claudio Chuaqui https://www.linkedin.com/in/claudio-chuaqui-5612381/
Andrew Coopersmith https://www.linkedin.com/in/andrew-s-coopersmith/
The Biotech Startups Podcast is handcrafted by our friends over at: fame.so
88 episoder
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