Does the Timing of Source Control in Sepsis Make a Difference?

Critical Care Perspectives in Emergency Medicine

The emergency department resuscitation of patients with sepsis focuses on early recognition, timely administration of appropriate antibiotics, appropriate fluid resuscitation, early vasopressor initiation for patients with sepsis-induced hypoperfusion, and hemodynamic monitoring. Source control is also an important component in the resuscitation of patients with sepsis. Though current guidelines identify source control as a "best practice" the optimal timing of source control remains uncertain. In this podcast, we discuss a recent study that evaluated the timing of source control with mortality in patients with community-acquired sepsis.