S01E07 Cancer Biology with Marc Mansour

Bolus: education delivered stat

Welcome to the formal launch episode of the 'Bolus' podcast! In this episode we are joined by Marc Mansour, a consultant haematologist specialising in the treatment of patients with Acute Leukaemias and Myelodyspastic Syndromes at UCLH. He is the research group leader of the Leukaemia Biology group at the UCL Cancer Institute, focusing on T-cell acute lymphoblastic leukaemia (T-ALL) and acute myeloid leukaemia (AML), and in particular on oncogenic transcription factor complexes, mechanisms of oncogenic enhancer formation, and novel drug targets. We start by discussing the seminal paper 'The Hallmarks of Cancer', and explore what processes begin to go wrong, in order for cancer to develop. DNA damage is a key driver in many cancers, but carcinogens are typically not the cause in many Haematological cancers, we discuss the reasons behind this. 'Bolus' explores the Haematology speciality, and has been created for nurses, junior doctors and allied healthcare professionals. It is made by three UCLH Haematology nurses, Sonia Thomas and Sarah Jordan, both ward sisters, and Gavin Cooper, a nurse educator. We will be releasing a new episode every Monday.