Bästa Healio podcaster (2024)

1
Lung Cancer Edition: Top Headlines for Week of November 11, 2024 10:57

11d ago10:57

10:57

In this edition, single-fraction SBRT outcomes for central lung tumors, adjuvant durvalumab extends survival in limited-stage small cell lung cancer and more. Read the full coverage here: Single-fraction SBRT confers ‘surprisingly excellent’ outcomes for central lung tumors Adjuvant durvalumab extends survival in limited-stage small cell lung cance…

1
The Story of the Flu Vaccine (Re-Release) 47:43

1M ago47:43

47:43

It's that time of year again, everyone rolling up their sleeves to get a flu shot. This throwback episode dives into the history of the struggles pinning down the causative agent of flu and the journey to the vaccine! Intro 0:40 In this episode 1:11 The history of the flu: 1892 1:41 What do we know about viruses? 6:29 Rabies and dead virus 11:17 A …

1
Lung Cancer Edition: Top Headlines for Week of October 14, 2024 10:45

1M ago10:45

10:45

In this edition, FDA approves Rybrevant for advanced lung cancer, screening orders in eligible patients higher with digital health program and more. Read the full coverage here: FDA approves Rybrevant for advanced lung cancer Lung cancer screening orders in eligible patients higher with digital health program FDA approves Opdivo regimen for resecta…

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Rheumatology/Psoriatic Arthritis Edition: Top Headlines for Week of September 23, 2024 11:48

2M ago11:48

11:48

In this edition, blue-collar workers more likely to miss work or quit due to psoriatic arthritis, infliximab biosimilar increase after release of a third option and more. Read the full coverage here: Blue-collar workers more likely to miss work, quit due to psoriatic arthritis Infliximab biosimilar uptake rapidly increased only after release of a t…

1
Lung Cancer Edition: Top Headlines for Week of September 16, 2024 13:55

2M ago13:55

13:55

In this edition, FDA approves first subcutaneous anti-PD-L1 cancer immunotherapy, ivonescimab ‘may be a new standard’ and more. Read the full coverage here: FDA approves first subcutaneous anti-PD-L1 cancer immunotherapy Ivonescimab extends PFS vs. pembrolizumab in advanced NSCLC, may be ‘a new standard’ Perioperative nivolumab improves outcomes in…

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DME/Retina Edition: Top Headlines for Week of September 9, 2024 8:40

2M ago8:40

8:40

In this edition, enrollment and dosing complete in phase 1 trial of AIV007, popular benchmarks in clinical practice guidelines and more. Read the full coverage here: Enrollment, dosing complete in phase 1 trial of AIV007 for AMD, diabetic macular edema OCT, visual acuity popular benchmarks in clinical practice guidelines for DME First patient dosed…

1
NSAIDs, Part 3: The rise, fall and rise again of COX-2 inhibition 37:44

3M ago37:44

37:44

In the third episode of the NSAIDs saga, we focus on COX-2 inhibition! Did the hopes and dreams of selective COX-2 inhibition pan out? What can the rise and fall of VIOXX teach us about physiology? Intro 0:11 Recap of part 1 & 2 0:28 In this episode 1:44 Cyclooxygenase 2 (COX-2) and the rat experiment 3:12 What do we know about the prostaglandins? …

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Rheumatology/Psoriatic Arthritis Edition: Top Headlines for Week of August 19, 2024 11:18

3M ago11:18

11:18

In this edition, drug discounts through Medicare price negotiations, opioid use has fallen 15% annually since 2014 and more. Read the full coverage here: Enbrel, Stelara to be discounted nearly 70% through Medicare price negotiations Opioid use has fallen 15% annually since 2014 in autoimmune rheumatic disease Inhibitor class PsO treatments exhibit…

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Lung Cancer Edition: Top Headlines for Week of August 12, 2024 15:14

3M ago15:14

15:14

In this edition, low education level raises follow-up risk in screening program, screening judgement strongly influenced by clinicians and more. Read the full coverage here: Low education level raises risk for loss to follow-up in lung cancer screening program Lung cancer screening judgement strongly influenced by clinicians Occupational benzene ex…

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DME/Retina Edition: Top Headlines for Week of August 5, 2024 11:23

4M ago11:23

11:23

In this edition, sozinibercept combination therapy shows durability, comparable improvements with aflibercept and more. Read the full coverage here: Sozinibercept combination therapy shows durability in patients with DME, neovascular AMD VIDEO: Comparable improvements seen with aflibercept 8 mg vs. 2 mg in DME DPP-IV, SGLT2 and GLP-1 drugs do not i…

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Rheumatology/Psoriatic Arthritis Edition: Top Headlines for Week of July 22, 2024 11:11

4M ago11:11

11:11

In this edition, guselkumab brings ‘stringent’ control through 2 years, SARDs outpatient visits result in opioid prescriptions and more. Read the full coverage here: Guselkumab brings active psoriatic arthritis into ‘stringent’ control through 2 years Nearly one-quarter of all SARDs outpatient visits in US result in opioid prescription FDA approves…

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Lung Cancer Edition: Top Headlines for Week of July 15, 2024 12:40

4M ago12:40

12:40

In this edition, atezolizumab benefits PD-L1-selected patients with NSCLC, risks persist with e-cigarette use after quitting tobacco smoking and more. Read the full coverage here: Adjuvant atezolizumab benefits PD-L1-selected patients with NSCLC Lung cancer risks persist with e-cigarette use after quitting tobacco smoking COPD, IPF end of life heal…

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DME/Retina Edition: Top Headlines for Week of July 8, 2024 10:22

5M ago10:22

10:22

In this edition, FDA approves Vabysmo prefilled syringe for retinal diseases, 4D Molecular Therapeutics updates on retinal disease candidates and more. Read the full coverage here: FDA approves Vabysmo prefilled syringe for retinal diseases VIDEO: 4D Molecular Therapeutics shares update on retinal disease candidates FDA approves Eylea biosimilar FY…

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Rheumatology/Psoriatic Arthritis Edition: Top Headlines for Week of June 24, 2024 10:14

5M ago10:14

10:14

In this edition, extensive psoriasis and IBD history predict difficult-to-treat psoriatic arthritis, targeted therapies demonstrate low risk for serious infection and more. Read the full coverage here: Extensive psoriasis, IBD history predict difficult-to-treat psoriatic arthritis Targeted psoriatic arthritis therapies demonstrate low risk for seri…

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NSAIDs, Part 2: The Dawn of the Anti-Inflammatories 46:59

5M ago46:59

46:59

In this episode, we dive into the story of aspirin and the development of ibuprofen, ending with the experiments that showed the mechanism of how aspirin actually works. Intro 0:12 Review of part 1 0:28 In this episode 1:04 Blocking prostaglandins and willow leaves 2:26 Edward Stone 3:45 Johann Andreas Buchner 4:16 The chemical structure of salicyl…

1
Lung Cancer Edition: Top Headlines for Week of June 17, 2024 15:04

5M ago15:04

15:04

In this edition, screening program identifies airways disease in previously undiagnosed COPD, positive results show benefits of subcutaneous bispecifics and more. Read the full coverage here: Lung cancer screening program identifies airways disease in previously undiagnosed COPD Positive results in lung cancer show benefits of subcutaneous bispecif…

1
DME/Retina Edition: Top Headlines for Week of June 3, 2024 10:27

6M ago10:27

10:27

In this edition, AI model helps predict anti-VEGF response in DME, Merck to acquire EyeBio and more. Read the full coverage here: VIDEO: AI model helps predict anti-VEGF response in diabetic macular edema Merck to acquire EyeBio VIDEO: IOP remains stable up to 48 weeks with aflibercept 8 mg for DME Phase 2 study of potential DME oral therapy meets …

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Rheumatology/Psoriatic Arthritis Edition: Top Headlines for Week of May 20, 2024 8:48

6M ago8:48

8:48

In this edition, difficult-to-treat psoriatic arthritis 'not all about the therapies', Samsung biosimilar comparable to etanercept and more. Read the full coverage here: Difficult-to-treat psoriatic arthritis 'not all about the therapies' Samsung biosimilar comparable to etanercept for psoriatic arthritis outcomes at 1 year Boehringer Ingelheim, Qu…

1
The Discovery of Non-Steroidal Anti-inflammatory Drugs (NSAIDs), Part 1 38:05

6M ago38:05

38:05

Humans have had an insatiable appetite for inhibiting production of prostaglandins for centuries! This series delves into the history of aspirin and NSAIDs, looking at the understanding of the prostaglandin pathway. · Intro 0:12 · In this episode 0:23 · What are NSAIDs? 0:53 · Prostaglandins 5:50 · What are prostaglandins? 7:19 · Where do prostagla…

1
Lung Cancer Edition: Top Headlines for Week of May 13, 2024 13:04

6M ago13:04

13:04

In this edition, smoking cessation support uptake at lung cancer screenings, glecirasib may deliver ‘efficacy and tolerability advantages’ and more. Read the full coverage here: Uptake of smoking cessation support high when offered at lung cancer screening Glecirasib may deliver ‘efficacy and tolerability advantages’ for KRAS-mutant lung cancer ‘Su…

1
DME/Retina Edition: Top Headlines for Week of May 6, 2024 9:54

7M ago9:54

9:54

In this edition, FDA accepts new drug application for Eluminex, most mentors in vitreoretinal subspecialty are men and more. Read the full coverage here: FDA accepts investigational new drug application for Eluminex DME treatment Most mentors in vitreoretinal subspecialty are men Carotid artery stenosis linked to retinal changes in patients with di…

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Rheumatology/Psoriatic Arthritis Edition: Top Headlines for Week of April 22, 2024 13:32

7M ago13:32

13:32

In this edition, FDA approves Selarsdi as Stelara biosimilar, deucravacitinib improves ‘broad range’ of patient-reported outcomes and more. Read the full coverage here: FDA approves Selarsdi as Stelara biosimilar for psoriasis, psoriatic arthritis Deucravacitinib improves ‘broad range’ of patient-reported psoriatic arthritis outcomes Advanced thera…

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Lung Cancer Edition: Top Headlines for Week of April 15, 2024 12:10

7M ago12:10

12:10

In this edition, durvalumab improves survival in limited-stage small cell lung cancer, most adults do not test homes for radon exposure and more. Read the full coverage here: Durvalumab improves survival in limited-stage small cell lung cancer Survey: Most adults do not test homes for radon exposure, unconcerned about risks FDA fast tracks investig…

1
Urticarial Vasculitis, Part 2: Walking the Balance Beam of Allergy and Rheumatology 35:59

7M ago35:59

35:59

This episode digs into the pathophysiology of urticaria vasculitis from anti-C1q to the story of bradykinin. · Intro 0:11 · In this episode 0:22 · Review of episode 83 1:23 · Listen to previous episode, The Complement System for Dunces 4:09 · Anti-C1q antibodies 6:26 · Lupus, anti-C1q and lupus nephritis 9:33 · What happens when you inject anti-C1q…

1
DME/Retina Edition: Top Headlines for Week of April 8, 2024 12:28

8M ago12:28

12:28

In this edition, PALADIN study navigates IOP-lowering surgery in DME patients, small-molecule eye drop well-tolerated as treatment for retinal vascular diseases and more. Read the full coverage here: PALADIN study: Navigating IOP-lowering surgery in DME patients for optimal outcomes Small-molecule eye drop safe, well-tolerated as treatment for reti…

1
Lung Cancer Edition: Top Headlines for Week of March 11, 2024 12:07

9M ago12:07

12:07

In this edition, race identified as risk factor for VTE, FDA approves Rybrevant for treatment of non-small cell lung cancer and more. Read the full coverage here: Race identified as risk factor for VTE after pulmonary resection for lung cancer FDA approves Rybrevant for treatment of non-small cell lung cancer Behavioral health disorders have a ‘big…

1
Urticarial Vasculitis: Attack of the Nettles, Part 1 26:07

9M ago26:07

26:07

Is it an allergy or an autoimmune vasculitis, or a little of both? Find out the story of urticarial vasculitis, how this disease was recognized and eventually sorted out from other types of urticaria. · Intro 0:12 · In this episode 0:21 · Case study 1:22 · Chronic spontaneous urticaria, hives and nettles 7:57 · Dermatographism and witchcraft? 10:15…

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Lung Cancer Edition: Top Headlines for Week of February 12, 2024 13:31

9M ago13:31

13:31

In this edition, blood test for lung cancer patients who may benefit from further immunotherapy, invasive procedures following lung cancer screenings and more. Read the full coverage here: Blood test identifies those with lung cancer who may benefit from further immunotherapy Invasive procedures rarely follow false-positive lung cancer screenings S…

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Lung Cancer Edition: Top Headlines for Week of January 15, 2024 10:49

10M ago10:49

10:49

In this edition, FDA places hold on cell therapy trial after patient death, selpercatinib delivers superior outcomes and more. Read the full coverage here: FDA places hold on trial of cell therapy for lung cancer after patient death Selpercatinib delivers superior outcomes, may ‘reduce the burden of NSCLC’ First-line immunotherapy benefits patients…

1
COVID-19, long COVID and the rheumatologist with Leonard Calabrese, DO 29:04

11M ago29:04

29:04

What should rheumatologists know about what we've learned about COVID-19 and long COVID in 2023? Hosted by Dr. Leonard Calabrese. · Intro 0:11 · In this episode 0:21 · 2023: current status and controversies 0:35 · What is going on with COVID-19? 01:53 · What do we know about vaccine responses? What should we be telling our patients about vaccines i…

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Dermatology Edition: Top Headlines for Week of December 18, 2023 8:09

11M ago8:09

8:09

In this edition, an advocacy group petitions the FDA for stronger safety warnings for Botox, melanoma regression is associated with improved prognosis and more. Read the full coverage here: Advocacy group petitions FDA for stronger safety warnings for Botox, related drugs Melanoma regression associated with improved prognosis Phase 4 results show V…

1
The Story of the Flu Vaccine 48:05

12M ago48:05

48:05

It's that time of year again, everyone rolling up their sleeves to get a flu shot. This episode dives into the history of the struggles pinning down the causative agent of flu and the journey to the vaccine! · Intro 0:12 · In this episode 0:17 · The history of the flu: 1892 3:10 · Rabies and dead virus 10:52 · A Sickness in the Serum, Part 2 14:31 …

1
Dermatology Edition: Top Headlines for Week of December 4, 2023 10:11

12M ago10:11

10:11

In this edition, allergic illnesses in children may be inherited from mothers; addressing needs of Muslim patients in dermatology; YouTube content on topical steroid withdrawal exhibits poor reliability and more. Read the full coverage here: Atopic dermatitis, other allergic illnesses in children may be inherited from mothers Addressing needs of Mu…

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Dermatology Edition: Top Headlines for Week of November 13, 2023 7:52

1y ago7:52

7:52

In this edition, dermatologists ‘uniquely positioned’ to aid human trafficking victims; FDA approves Cosentyx for hidradenitis suppurativa and more. Read the full coverage here: Dermatologists ‘uniquely positioned’ to recognize, aid human trafficking victims FDA approves Cosentyx as first IL-17A inhibitor for hidradenitis suppurativa FDA approves S…

1
It's in the Air: Silica exposure and the risk of autoimmunity, Part 4 23:38

1y ago23:38

23:38

What is silica? How does it impact your risk of developing autoimmunity if you inhale it, inject it or even snort it up your nose? Listen and find out! · Intro 0:12 · In the previous episodes 0:28 · The Ajax incident of 1979 1:15 · Silica and its association with autoimmune disease 4:11 · The history of silica and the health risks 5:21 · Rheumatoid…

1
Prostate Cancer Edition: Top Headlines for Week of November 6, 2023 10:48

1y ago10:48

10:48

In this edition, multicancer detection tests show promise; lifestyle counseling appointments benefit cancer survivors; use of low-value drugs for patients with cancer, and more. Read the full coverage here: Multicancer detection tests show promise, but questions linger about their accessibility Shared medical appointments for lifestyle counseling b…

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Dermatology Edition: Top Headlines for Week of October 30, 2023 11:50

1y ago11:50

11:50

In this edition, FDA approves Bimzelx for plaque psoriasis; roflumilast foam improves quality of life in patients with seborrheic dermatitis and more. Read the full coverage here: FDA approves Bimzelx for treatment of moderate to severe plaque psoriasis Roflumilast foam improves quality of life in patients with seborrheic dermatitis Opzelura effect…

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Autoimmunity, Part 3: The Lupus Gradient 45:07

1y ago45:07

45:07

In this episode, we dig through the data of lupus in Africa and speak with experts on the Lupus Gradient, the impact of malaria and what we can learn from it all. · Intro 0:12 · In the previous episode 0:30 · Lupus Gradient 2:01 · Back to Dr. Brian Greenwood 3:48 · Polyarthritis 4:04 · Rates of autoimmune diseases 6:00 · Malaria and mouse models 7:…

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Dermatology Edition: Top Headlines for Week of October 16, 2023 8:34

1y ago8:34

8:34

In this edition, FDA issues complete response letter for relabotulinumtoxinA; mucocutaneous manifestations may signal COVID-induced inflammatory disease in children and more. Read the full coverage here: FDA issues complete response letter for relabotulinumtoxinA for frown lines, crow’s feet Mucocutaneous manifestations may signal COVID-induced inf…

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Prostate Cancer Edition: Top Headlines for Week of October 9, 2023 13:40

1y ago13:40

13:40

In this edition, precision navigators reduce racial disparities in genomic testing; cancer diagnoses fell sharply during early days of pandemic; Prostate Cancer Awareness Month updates, and more. Read the full coverage here: Precision navigators reduce racial disparities in genomic testing for prostate cancer Cancer diagnoses fell sharply during ea…

1
Dermatology Edition: Top Headlines for Week of October 2, 2023 12:26

1y ago12:26

12:26

In this edition, retinoids and OTC products for photoaged skin; fractional lasers show promise in skin cancer prevention; a botanical drug for severe thermal burns and more. Read the full coverage here: Prescription retinoids, OTC products positively impact photoaged skin Fractional lasers show promise in skin cancer prevention Botanical drug may o…

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Dermatology Edition: Top Headlines for Week of September 18, 2023 12:36

1y ago12:36

12:36

In this edition, CDC issues a health advisory concerning flesh-eating bacterium, staging for melanoma does not represent accurate recurrence and mortality and more. Read the full coverage here: CDC issues health advisory about recent reports of fatal Vibrio vulnificus Study finds melanoma treatment costs have increased, but so has survival Melanoma…

1
Dermatology Edition: Top Headlines for Week of September 4, 2023 11:30

1y ago11:30

11:30

In this edition, nearly $1 million in grants to aid diversity, equity, inclusion research; topical halcinonide may benefit patients with psoriasis; Asian patients may experience earlier mycosis fungoides diagnosis and more. Read the full coverage here: Nearly $1 million in grants to aid dermatology research in diversity, equity, inclusion Topical h…

1
Prostate Cancer Edition: Top Headlines for Week of August 28, 2023 13:54

1y ago13:54

13:54

In this edition, ‘equitable access’ to care may reduce racial disparities in survival; exercise may improve sexual function among men with prostate cancer; image-guided adaptive prostate radiation therapy for short-term toxicities, and more. Read the full coverage here: ‘Equitable access’ to care may reduce racial disparities in prostate cancer sur…

1
Dermatology Edition: Top Headlines for Week of August 21, 2023 10:15

1+ y ago10:15

10:15

In this edition, M-PDT efficacy similar to isotretinoin in acne vulgaris; Spitz neoplasm diagnosis in adults; immunotherapy treatment shows promise in basal cell carcinoma and more. Read the full coverage here: M-PDT efficacy similar to isotretinoin in acne vulgaris Clinicians should not ‘shy away’ from a Spitz neoplasm diagnosis in adults Novel no…

1
The Geography of Autoimmunity, Part 2 38:29

1+ y ago38:29

38:29

This episode delves into what we can learn about the impact of the environment on autoimmunity, digging into how rates of autoimmunity can vary drastically in different parts of the world. · Intro 0:12 · In this episode 0:16 · Dr. Brian Greenwood 0:22 · The geography of autoimmunity 7:01 · Type 1 diabetes 10:31 · Finland and type 1 diabetes 13:57 ·…

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Dermatology Edition: Top Headlines for Week of August 7, 2023 10:49

1+ y ago10:49

10:49

In this edition, nonalcoholic muscadine wine may improve aging skin; atopic disease risk increases in sexually diverse patients; AI doubles diagnostic accuracy among patients with skin of color and more. Read the full coverage here: Nonalcoholic muscadine wine may improve aging skin in older women Atopic disease risk increases in sexually diverse p…

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Leukemia Edition: Top Headlines for Week of July 31, 2023 11:39

1+ y ago11:39

11:39

In this edition, FDA approves Vanflyta for newly diagnosed AML; liso-cel could have ‘best shot’ at remission for double refractory CLL; mortality factors among cancer survivors and more. Read the full coverage here: FDA approves Vanflyta for newly diagnosed acute myeloid leukemia VIDEO: Liso-cel could have ‘best shot’ at remission for double refrac…

1
Dermatology Edition: Top Headlines for Week of July 24, 2023 10:10

1+ y ago10:10

10:10

In this edition, lack of sunless tanner education may cause confusion; intralesional HPV vaccine may clear recalcitrant warts; Ilumetri improves well-being of patients with plaque psoriasis and more. Read the full coverage here: Lack of sunless tanner education may cause diagnostic confusion, UV exposure Intralesional HPV vaccine may clear recalcit…

1
Leukemia Edition: Top Headlines for Week of July 17, 2023 11:56

1+ y ago11:56

11:56

In this edition, obesity linked to adverse outcomes among AYAs; pirtobrutinib produces high response rates; CDC study reveals overall increase in pediatric cancer incidence and more. Read the full coverage here: Overweight, obesity linked to adverse outcomes among AYAs treated for leukemia Pirtobrutinib produces high response rates in heavily pretr…

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