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The Addiction Files: An Addiction Medicine Podcast

Darlene Petersen, MD and Paula Cook, MD

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Darlene Petersen, MD and Paula Donnelly Cook, MD are board certified addiction medicine and family medicine physicians providing evidence based education, clinical pearls and resources to physicians, residents and students while striving to destigmatize the treatment of addiction in our medical culture and save lives. Tune in to learn about the latest treatments for all things addiction. Join us as we conduct expert interviews, review clinical pearls and best practices and discuss the latest ...
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Addiction Medicine Podcast

Governor's Institute

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The Addiction Medicine Podcast is designed for healthcare professionals and others interested in addiction medicine and will feature thoughtful conversations and insights from clinicians, patients and families, policymakers and other stakeholders.
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The Curbsiders Addiction Medicine Podcast

The Curbsiders Addiction Medicine Podcast

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SEASON 2 will launch July 6th, 2023! Step up your knowledge on caring for patients with substance use disorders (SUD)! This show features addiction medicine experts who are dedicated to bringing you practice changing knowledge about substance use, and substance use disorders. We use expert interviews to demystify common addiction medicine topics, reduce stigma, and inspire listeners to be fierce advocates for all individuals who use substances. This mini-series is hosted by Doctors Carolyn C ...
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Addiction Medicine: Beyond the Abstract

American Society of Addiction Medicine

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An ideal opportunity for those interested in addiction medicine to get a closer look at the perspectives behind formal research articles. Podcasts offer insights into the experiences of the authors and researchers behind the great work and development in the field. Listening to their stories and thought processes helps listeners to connect with the experts behind the journal in a brand-new way. Hosted by Journal Podcast Editor, Shawn McNeil, MD
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Anna Lembke, MD joins us to discuss the Dopamine reward system in our brains and how the pleasure/pain balance affects addiction and recovery. This is a fascinating discussion. Hosted by Paula Donnelly Cook, MD and Darlene Petersen, MD. For more information on Dr. Lembke: www.annalembke.com Check out her New York Times best seller books "Dopamine N…
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In this episode we discuss improvements in cognitive function with opioid abstinence. Kaur, G. Et Al. Effects of Abstinence From Opioid on Neuropsychological Performance in Men With Opioid Use Disorder: A Longitudinal Study. Journal of Addiction Medicine 17(5): p 557-562, 9/10 2023. We also talk about paramedics giving buprenorphine along with nalo…
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Does varenicline reduce alcohol cravings? Tune in as we review the evidence, mechanism of action of varenicline. Hosted by Paula Donnelly Cook, MD and Darlene Petersen, MD. Check us out on facebook @Theaddictionfiles; X @THEADDICTIONFI1, TikTok, or Instagram @Theaddictionfiles or email us at theaddictionfiles@gmail.com No explicit language but this…
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Articles that Changed Our Practice-Part 2 In this episode we discuss 5 more articles that changed our addiction medicine practice. Chambers LC, et al. Buprenorphine Dose and Time to Discontinuation Among Patients With Opioid Use Disorder in the Era of Fentanyl. JAMA Netw Open. 2023; 6(9):e2334540. September 2023. (Episode 34) Caponnetto, P., et al.…
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Mason Turner, MD returns to discuss depression and substance use disorders as part of our mental health and substance use disorders series. Dr. Turner gives us a primer on the types of depression, epidemiology of depression in substance using populations, treatment considerations and lifestyle interventions. Hosted by Darlene Petersen, MD and Paula…
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Articles that Changed Our Practice-Part 1 In this episode we discuss 5 articles that changed our addiction medicine practice. Mahdi Sheikh, et al. Postdiagnosis Smoking Cessation and Reduced Risk for Lung Cancer Progression and Mortality: A Prospective Cohort Study. Ann Intern Med.2021;174:1232-1239. [Epub 27 July 2021]. (Episode 4) Santos GM, et a…
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Steve Sugden, MD joins us to discuss lifestyle medicine and neuroplasticity in the recovery process. Hosted by Paula Donnelly Cook, MD and Darlene Petersen, MD. Check us out on facebook @Theaddictionfiles or twitter @THEADDICTIONFI1 or Instagram Theaddictionfiles or email us at theaddictionfiles@gmail.com No explicit language but this podcast discu…
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In episode 38 we discuss an article comparing different treatments (and no treatment) for opioid use disorder. Robert Heimer, Anne C. Black, Hsiuju Lin, Lauretta E. Grau, David A. Fiellin, Benjamin A. Howell, Kathryn Hawk, Gail D’Onofrio, William C. Becker. Receipt of Opioid Use Disorder Treatments Prior to Fatal Overdoses and Comparison to No Trea…
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George Koob, PhD director of NIAAA teaches us about the addiction cycle, the origins of "Hyperkatefia", review of treatment options during the negative affect cycle and how NIAAA is monitoring current policies and trends regarding alcohol use. Hosted by Paula Cook, MD and Darlene Petersen, MD. www.niaaa.nih.gov https://www.rethinkingdrinking.niaaa.…
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37. Injectable Vs. Sublingual Buprenorphine In episode 37 we discuss an article comparing injectable and sublingual buprenorphine. Superiority and cost-effectiveness of monthly extended-release buprenorphine versus daily standard of care medication: a pragmatic, parallel-group, open-label, multicentre, randomised, controlled, phase 3 trial. Marsden…
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Podcast host Shawn McNeil, MD, is joined by Joshua Sharfstein, MD, and Sara Whaley, MPH, from Johns Hopkins Bloomberg School of Public Health who delve into the strategic allocation of $56 billion from opioid litigation settlements. As they discuss the principles for effective fund utilization, they highlight opportunities for addiction medicine sp…
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Lucinda Grande MD, FASAM joins us to discuss her research on low dose ketamine for buprenorphine inductions with emphasis on transitions from fentanyl to buprenorphine. She discusses patient selection, dosing considerations, and safety profile. Hosted by Paula Donnelly Cook, MD and Darlene Petersen, MD. Check us out on facebook @Theaddictionfiles o…
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In episode 36 we discuss an article about the mediators of problematic smartphone use. Christiane Arrivillaga, Caleb J. Hallauer, Christian Montag, Jon D. Elhai. Emotion dysregulation factors associated with problematic smartphone use severity: The mediating role of fear of missing out. Addictive Behaviors. Volume 143. 2023. https://doi.org/10.1016…
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Dr. Javier Ballester joins us for our second episode on co-occurring mental health and substance use. We'll cover Bipolar, its prevalence with substance use disorders, diagnosis, and treatment considerations. Hosted by Paula Donnelly Cook, MD and Darlene Petersen, MD. Check us out on facebook @Theaddictionfiles or twitter @THEADDICTIONFI1 or Instag…
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In episode 35 we discuss whether eliminating prior auths leads to more buprenorphine prescribing. Christine PJ, Larochelle MR, Lin L, McBride J, Tipirneni R. Removal of Medicaid Prior Authorization Requirements and Buprenorphine Treatment for Opioid Use Disorder. JAMA Health Forum. 2023;4(10):e233549. We also discuss buprenorphine diversion, and th…
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Our year-end review in addiction medicine for 2023, covers key topics, including the 2022 NSDUH data, trends in xylazine and fentanyl, and the impact of social isolation on alcohol use. Hosted by Paula Donnelly Cook, MD and Darlene Petersen, MD. Check us out on facebook @Theaddictionfiles or twitter @THEADDICTIONFI1 or Instagram Theaddictionfiles o…
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In episode 24 we discuss prescribing 24 mg of buprenorphine daily. Chambers LC, Hallowell BD, Zullo AR, et al. Buprenorphine Dose and Time to Discontinuation Among Patients With Opioid Use Disorder in the Era of Fentanyl. JAMA Netw Open. 2023;6(9):e2334540. September 2023. We also discuss why Rite Aid filed for bankruptcy, and the FDA ban on mentho…
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In episode 28 of Addiction Medicine: Beyond the Abstract, host Shawn McNeil, MD is joined my Ashish Thakrar, MD, MS, an addiction medicine specialist and Assistant Professor of Medicine with the University of Pennsylvania. Dr. Thakrar discusses the outcome of his research, which aimed to determine whether fentanyl concentration is associated with t…
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We are excited to launch the first in our series on cooccurring mental health disorders and substance use disorders. Dr. Mason Turner joins us to discuss the prevalence of anxiety disorders in the substance using population. Types of anxiety disorders seen, treatment considerations and common pitfalls to avoid when managing patients with cooccurrin…
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In episode 33 we discuss overdose risk and polypharmacy: opioids, benzodiazepines, antipsychotics, and gabapentinoids. Domzaridou E, Carr MJ, Millar T, Webb RT, Ashcroft DM. Non-fatal overdose risk associated with prescribing opioid agonists concurrently with other medication: Cohort study conducted using linked primary care, secondary care and mor…
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We are discussing inhalant misuse, epidemiology, diverse routes of administration, the spectrum of substances subjected to misuse, and the ensuing ramifications, spanning both acute and chronic side effects. We review a spectrum of treatment modalities, ranging from emergency interventions and withdrawal management. Hosted by Paula Cook, MD and Dar…
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In episode 32 we discuss an article about trazodone for sleep in people with opioid use disorder on buprenorphine. Piyush Goyal, Dheeraj Kattula, Ravindra Rao, Roshan Bhad, Ashwani Kumar Mishra, Anju Dhawan. Trazodone for sleep disturbance in opioid dependent patients maintained on buprenorphine: A double blind, placebo-controlled trial. Drug and A…
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This week we review the journal article "Buprenorphine Dose and Time to Discontinuation Among Patients With Opioid Use Disorder in the Era of Fentanyl." how do we manage patients on high dose synthetic opioids. Hosted by Paula Cook, MD and Darlene Petersen, MD. "Buprenorphine Dose and Time to Discontinuation Among Patients With Opioid Use Disorder …
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31: We discuss an article about how naloxone training impacts IV drug use. Colledge-Frisby S, Rathnayake K, Nielsen S, et al. Injection Drug Use Frequency Before and After Take-Home Naloxone Training. JAMA Netw Open. 2023;6(8):e2327319. We also discuss gambling self-exclusion and which professions use the most drugs. From the Pennsylvania Gaming Co…
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Kathie Supiano, PhD, LCSW, F-GSA, FT, APHSW-C joins us in this poignant episode to discuss the grief of overdose death. We review how loss isolates those involved including healthcare workers. Dr. Supiano expertly walks us through this process. This is a can't miss episode hosted by Paula Cook, MD and Darlene Petersen, MD. http://grasphelp.org/ GRA…
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Quick summaries of Episodes 21-30. 21. SOAT for OUD: Short-Acting Opioid Agonists for Opioid Use Disorder: Safety and preliminary outcomes of short-acting opioid agonist treatment (sOAT) for hospitalized patients with opioid use disorder 22. Contingency Management for Coronary Artery Disease: High-risk Coronary Plaque Regression in Cash-based Conti…
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The language used to describe people with substance use disorder impacts stigma and influences clinical decision-making. Host Dr. Shawn McNeil, MD discusses with Dr. Scott G. Weiner, MD the presence of stigmatizing language in clinical notes and detects patient- and provider-level differences. ----more---- Based on original research published in th…
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The language used to describe people with substance use disorder impacts stigma and influences clinical decision-making. Host Dr. Shawn McNeil, MD discusses with Dr. Scott G. Weiner, MD the presence of stigmatizing language in clinical notes and detects patient- and provider-level differences. Based on original research published in the Journal of …
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Keep saving lives by prescribing methadone and buprenorphine. Learn how initiations of each have changed in the era of high-potency synthetic opioids (HPSOs) like fentanyl and how to continue to provide person-centered care to people with opioid use disorder. We’re joined by Dr Melissa Weimer, @DrMelissaWeimer (Yale University). This episode is in …
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Overamping, what is it, who is most vulnerable, how do you recognize it and what are some of the treatment considerations. Tune in to this fascinating discussion on this emerging trend. Hosted by Paula Cook, MD and Darlene Petersen, MD. Resources SAMHSA TIP 33 Check us out on facebook @Theaddictionfiles or twitter @THEADDICTIONFI1 or Instagram Thea…
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In episode 30 we discuss an article about racial differences in the receipt of medications for opioid use disorder. Barnett ML, Meara E, Lewinson T, Hardy B, Chyn D, Onsando M, Huskamp HA, Mehrotra A, Morden NE. Racial Inequality in Receipt of Medications for Opioid Use Disorder. N Engl J Med. 2023 May 11;388(19):1779-1789. We also talk about opioi…
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Dr. Robert Simpson and Kelli Jacobsen, LCSW join us for an important discussion regarding professional health programs. We review the common myths surrounding PHP's (professional health programs), who qualifies, benefits and some of the barriers that still exist. Hosted by Paula Cook, MD and Darlene Petersen, MD. Resources: If you are a health prof…
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In episode 29 we discuss an article about using varenicline and counseling for vaping cessation.. Caponnetto, P., Campagna, D., Ahluwalia, J.S. et al. Varenicline and counseling for vaping cessation: a double-blind, randomized, parallel-group, placebo-controlled trial. BMC Med 21, 220 (2023). In other vaping-related news: From NYSCSH: Vape pens tha…
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Prevent opioid overdoses in your community! We discuss opioid overdose prevention and treatment so you can counsel patients who use substances on ways to decrease their risk of overdose. We discuss optimal ways to respond to hospital overdoses, ideal doses of naloxone, and how to monitor a patient experiencing an overdose clinically. We’re joined b…
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We just got back from CSAM’s (California Society of Addiction Medicine) Annual Conference 2023 and we have the highlights for you. We discuss topics surrounding fentanyl, harm reduction, neurobiology of addiction, alcohol use disorders and more. Hosted by Paula Cook, MD and Darlene Petersen, MD. Check us out on facebook @Theaddictionfiles or twitte…
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In this episode, Dr. Cynthia Kuhn gives an update on cannabis in North Carolina and talks about 'New Drugs on the Radar' at the 2023 Addiction Medicine Conference in Asheville, NC. Dr. Kuhn is a Professor in the Department of Pharmacology and Cancer Biology, Professor of Psychiatry and Behavioral Sciences and Professor of Psychology and Neuroscienc…
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This presentation, 'Evolution of Fentanyl: Understanding the Relevance of Xylazine' was given at the 2023 Addiction Medicine Conference in Asheville, North Carolina by Robyn Jordan, MD, PhD and Zoe McElligott, PhD. Dr. Jordan is a Board-Certified Psychiatrist and Addiction Medicine Specialist and is an Assistant Professor at the University of North…
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Episode 4 is a presentation from the 2023 Addiction Medicine Conference in Asheville, North Carolina from Dr. Jon Zibbell, a senior scientist in the Center for Behavioral Health Epidemiology, Implementation & Evaluation Research at RTI International. It's titled, 'Emerging Trends in Overdose Mortality Against the Backdrop of Growing Fentanyl and Me…
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Accelerate your knowledge on low-dose buprenorphine starts for individuals with opioid use disorder. We cover the physiology of how low-dose starts work, different 4-7 day protocols, and how to troubleshoot challenges patients may face. We’re joined by Dr. Eleasa Sokolski, MD (Oregon Health and Sciences University) and Amelia Goff, MSN, FNP (Oregon…
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In this episode of our 3-part series on recent changes to the rules around who can prescribe buprenorphine, we get answers to questions that providers and pharmacists may have about these changes. Thanks for listening! Get more of our addiction medicine-related content and learn about the work we do with Veterans, service members and military famil…
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Now that all practitioners who have a current DEA registration that includes Schedule III authority can prescribe buprenorphine for Opioid Use Disorder, pharmacies may now see an increase in the number of prescriptions for the life-saving medication. In this second episode we talk with Dr, Cheryl Viracola, Director of Practice Advancement for the N…
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We're kicking off Season 3 of the Addiction Medicine Podcast with a hot topic - buprenorphine. Over the last year, there have been important changes in requirements related to prescribing buprenorphine for the treatment of opioid use disorder. To better understand these changes, we talk to Dr. Blake Fagan, Clinical Director of Substance Use Disorde…
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In episode 28 we discuss an article about pain and addiction recovery. Ajay Manhapra, Elina A. Stefanovics, Taeho Greg Rhee, Robert A. Rosenheck, Persistence of significant pain interference following substance use disorder remission: Negative association with psychosocial and physical recovery, Drug and Alcohol Dependence, Volume 232, 2022, 109339…
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Gain insight into how racialized US drug policies, the War on Drugs, and media portrayals of substance use impact our patients in ongoing ways. Learn how you can take action and intentionally promote equity as a clinician! We’re joined by Dr Myra Mathis, @DrMyraMathis (University of Rochester Medical Center) Claim free CME for this episode at curbs…
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In this episode, we are delighted to be joined by Nobi and Charles "Chuck" Pyle, who engage in a comprehensive conversation on the fascinating world of 5NP, or five needle acupuncture. Together, we delve into the rich historical background of 5NP, exploring its prominent applications such as addressing addiction and trauma. Furthermore, our guests …
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Learn about long-acting injectable (LAI) buprenorphine for the treatment of opioid use disorder with Dr. Ken Lee, an addiction medicine provider in Canada. We go over the basics of using LAI buprenorphine, tips and tricks for troubleshooting with patients as well as newer protocols that Dr. Lee and his colleagues use. Claim free CME for this episod…
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In episode 27 we discuss an article about the risk of developing opioid use disorder after the first opioid prescription. Kendler, K., Lönn, S., Ektor-Andersen, J., Sundquist, J., & Sundquist, K. (2022). Risk factors for the development of opioid use disorder after first opioid prescription: A Swedish national study. Psychological Medicine, 1-9. Fr…
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Jumpstart your knowledge on how to counsel patients in primary care to help decrease their risk of returning to substance use! Learn how to help patients identify triggers, develop plans on how to navigate high-risk situations & so much more! We are joined by psychologist Dr. Eve Lasswell PsyD at the University of California San Diego! Claim free C…
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Last week of August is Overdose Prevention Awareness week. We review overdose statistics, risk factors, vulnerable populations and prevention. Hosted by Paula Cook, MD and Darlene Petersen, MD. Check us out on facebook @Theaddictionfiles or twitter @THEADDICTIONFI1 or Instagram Theaddictionfiles or email us at theaddictionfiles@gmail.com No explici…
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Interpret urine drug tests (UDT) like a toxicologist! Learn how to approach interpreting positive opiates, opioids, and benzodiazepines in UDT. We discuss the nuances of interpreting UDT, false positives, and how to counsel a patient prior to ordering the test. We’re joined by Dr. Timothy Weigand @TwToxMD (University of Rochester Medical Center). C…
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